Anti-Tenascin antibody produced in chicken, affinity isolated antibody, buffered aqueous solution

Application

Anti-Tenascin antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200. It is also used for immunohistology.

Biochem/physiol Actions

Tenascin-C (TNC) is an extracellular matrix protein that is expressed at low levels in normal adult tissue but is highly expressed around many tumors including ovarian tumors. High levels are observed in many diseases like heart failure, thrombosis, atherosclerosis and cancer. It plays an indispensable role in tumor development. Expression of this gene is induced by growth factors as well as mechanical strain in fibroblast. It is up-regulated within glioma tissues and cultured glioma cell lines. TNC possesses a multi-modular structure with a variety of functional properties.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Immunogen Sequence: GI # 4504549, sequence 18-175

Recombinant tenascin C (hexabrachion)

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.